Association of P2X7R Functional Expression and Gene Polymorphisms with Systemic Lupus Erythematosus
نویسندگان
چکیده
منابع مشابه
Association of P2X7R Functional Expression and Gene Polymorphisms with Systemic Lupus Erythematosus
Objective: To investigate P2X purinoceptor 7 (P2X7R) expression changes on peripheral blood mononuclear cell (PBMC) surfaces of systemic lupus erythematosus (SLE) patients as well as their association with serum cytokine levels and patients’ clinical features. In addition, the effects of different P2X7R single nucleotide polymorphisms (SNPs) on P2X7R expression and cytokine production were inve...
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Gamma-aminobutyric acid receptor subunit pi (GABRP) is involved in inhibitory synaptic transmission in the central nervous system. This gene encodes multisubunit chloride channels and is also expressed in numerous nonneuronal tissues such as the uterus and the ovaries. This study was aimed to validate whether the polymorphisms in the GABRP gene are associated with the susceptibility to systemat...
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ژورنال
عنوان ژورنال: Journal of Clinical & Medical Genomics
سال: 2015
ISSN: 2472-128X
DOI: 10.4172/2472-128x.1000131